80% Nylon, 20% Spandex Truform 8845; Medical support hose; Unisex style durable knit; 30-40 strength graduated compression Soft top will not constrict leg; Defined heel enhances fit; Roomy comfort toe for sensitive feet Use for severe symptoms related to circulatory and vascular conditions as directed by a doctor Treats ulcers, varicose veins, lymph edema, DVT, thrombotic PTS, sclerotherapy, blood clot embolism Made in the USA; Measure according to size chart; Latex-Free; Nylon and Spandex construction