Biomedical instrumentation is the application of knowledge and technologies to solve problems related to living biological systems. It involves diagnosis, treatment and prevention of disease in human. As the medical field is emerging, the area of Biomedical Engineering is an expanding field. We use the term “bio” to denote something related to life. When basics of physics and chemistry get applied to the living things, and we name them as Biophysics and Biochemistry. So when the discipline of engineering and medicine interacts, it is called Biomedical Engineering.It involves measurement of biological signals like ECG, EMG, or any electrical signals generated in the human body. Biomedical Instrumentation helps physicians to diagnose the problem and provide treatment. To measure biological signals and to design a medical instrument, concepts of electronics and measurement techniques are needed.